Overview of PopED

PopED 2.x is a Optimal Experimental Design tool for Non-Linear Mixed Effect Models.

PopED 2.x is based on Matlab scripts and, for Windows .NET users or Mono users, a Graphical User Interface (GUI) is available.

The PopED GUI is a Windows based program written in the language C# .NET 2.0 that will wrap around the script version of PopED (written in Matlab) that performs the calculations needed to get an optimal design. The purpose of the GUI is to get an easy way to build up an experiment and to optimize the design variables in that experiment. There are also tools available for interpretation of the outcome of the optimal design and ways to validate models and simulate models prior to the optimal design. All these tools are accessible via the script version of PopED but then the user needs knowledge about the Matlab programming language and how to set up an experiment in the Matlab environment, therefore the GUI was developed to minimize the skills needed by the user in terms of programming. The PopED GUI also provides model templates and examples that will help the user to set up their own experiments. Some knowledge in the Matlab language might be useful but the model templates should give a good introduction to defining PopED models in Matlab.

The PopED development team consists of Joakim Nyberg, Sebastian Ueckert, Mats O. Karlsson and Andrew Hooker, and is based at the Pharmacometrics research group, within the Department of Pharmaceutical Biosciences at Uppsala University.

PopED 2.x is (c) 2009 Joakim Nyberg, Sebastian Ueckert, Mats O. Karlsson and Andrew Hooker. All rights reserved.